MIDATECH PHARMA
R&D | HCC

Liver cancer is the third leading cause of cancer deaths worldwide, affecting approximately 500,000 people. Prognosis is poor since if the tumour cannot be surgically resected – as is the problem in up to 80% of cases - then patients usually do not survive beyond 6 months.  Midatech GNP’s are being developed to repurpose and improve existing therapies for liver cancer. By attaching targeting motifs together with chemotherapeutics on the same GNP, it is possible to alter the biodistribution of toxic chemotherapeutics to focus on the tumour and spare normal tissues. This shift in biodistribution can significantly improve the therapeutic index of treatments for this devastating disease.

MTD119 (previously MTR104 in research) will now enter formal investigational new drug (IND) application enabling studies, with completion expected in H1 2018. This will be followed by an expected IND submission to the US Food and Drug Administration for first in human studies to commence in 2018. 

R&D
R&D
HCC

Liver cancer is the third leading cause of cancer deaths worldwide, affecting approximately 500,000 people. Prognosis is poor since if the tumour cannot be surgically resected – as is the problem in up to 80% of cases - then patients usually do not survive beyond 6 months.  Midatech GNP’s are being developed to repurpose and improve existing therapies for liver cancer. By attaching targeting motifs together with chemotherapeutics on the same GNP, it is possible to alter the biodistribution of toxic chemotherapeutics to focus on the tumour and spare normal tissues. This shift in biodistribution can significantly improve the therapeutic index of treatments for this devastating disease.

MTD119 (previously MTR104 in research) will now enter formal investigational new drug (IND) application enabling studies, with completion expected in H1 2018. This will be followed by an expected IND submission to the US Food and Drug Administration for first in human studies to commence in 2018. 

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